Human Genetics: Concepts and Applications (Lewis), 9th EditionNew to This EditionNew and updated information is integrated throughout the chapters, and a few features from past editions have been moved. Highlights from the revision are included here. Chapter 1 Overview of Genetics■ Updates on the Genetic Information Nondiscrimination Act and the Human Microbiome Project ■ New Figure 1.8 Diseasome—diseases are connected in unexpected ways ■ New Bioethics: Choices for the Future, “Genetic Testing and Privacy”Chapter 2 Cells ■ Stem cell coverage now stresses reprogrammed cells, with two new figures and a new Bioethics: Choices for the Future, “Should You Bank Your Stem Cells?” ■ New In Their Own Words, “A Little Girl with Giant Axons”Chapter 4 Single-gene Inheritance ■ New chapter opener “His Daughter’s DNA,” about a father’s quest to solve a genetic mystery ■ New section 4.1, A Tale of Two FamiliesChapter 5 Beyond Mendel’s Laws ■ New Reading 5.1, “The Genetic Roots of Alzheimer Disease” ■ New Table 5.3, Types of Genetic MarkersChapter 6 Matters of Sex ■ New chapter opener, “A Controversial Hypothesis: Mental Illness, Mom, and Dad” ■ New Reading 6.2, “Rett Syndrome—A Curious Inheritance Pattern”Chapter 7 Multifactorial Traits ■ New Figure 7.1, Anatomy of a trait—rare single-gene disorders versus common SNP patterns ■ New section 7.4, Genome-wide association studies (including new figures 7.9 and 7.11)Chapter 8 Genetics of Behavior ■ New section 8.5, How nicotine is addictive and raises cancer risk ■ New section 8.8, Autism (includes new Figure 8.9, Understanding autism)Chapter 9 DNA Structure and Replication ■ New Bioethics: Choices for the Future, “Infidelity Testing”Chapter 11 Gene Expression and Epigenetics ■ New Figure 11.7, Control of gene expression (transcription factors and microRNAs) ■ New text on the evolving definition of a geneChapter 12 Gene Mutation ■ New chapter opening case study, “The Amerithrax Story” ■ New Figure 12.1, Animal models of human diseases ■ New Figure 12.11, Using copy number variants in healthcareChapter 13 Chromosomes ■ New Bioethics: Choices for the Future, “The Denmark Study: Screening for Down Syndrome”Chapter 16 Human Ancestry ■ New Bioethics: Choices for the Future, “Indigenous Peoples” ■ Expanded coverage of markers, haplogroups, and migration ■ New Reading 16.2 “Should You Take a Genetic Ancestry Test?”Chapter 17 Genetics of Immunity ■ Shortened and reorganized to stress geneticsChapter 18 Genetics of Cancer ■ New Table 18.2, Processes and Pathways Affected in Cancer ■ The cancer genomeChapter 19 Genetic Technologies: Amplifying, Modifying, and Monitoring DNA ■ Expanded and updated information on DNA patents ■ New section 19.5, Silencing DNA (RNAi, antisense, and knockouts)Chapter 20 Genetic Testing and Treatment ■ New section 20.1, “Geneticists find zebras, and some horses” (including new figure 20.1) ■ New information on direct-to-consumer tests and CLIA regulations ■ Gene therapy to treat hereditary blindness in an 8-yearoldChapter 22 Genomics ■ New chapter opener, “20,000 Genomes and Counting” ■ New Reading 22.1, “The First Three Humans to Have Their Genomes Sequenced" |  |
